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Soft fibrin gels promote selection and growth of tumourigenic cells
The identification of stem-cell-like cancer cells through conventional methods that depend on stem-cell markers is often unreliable. We developed a mechanical method of selecting tumourigenic cells by culturing single cancer cells in fibrin matrices of ~100 Pa in stiffness. When cultured within thes...
Asıl Yazarlar: | , , , , , , , , , |
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Materyal Türü: | Online Makale Metin |
Dil: | English |
Baskı/Yayın Bilgisi: |
2012
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Konular: | |
Online Erişim: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405191/ https://www.ncbi.nlm.nih.gov/pubmed/22751180 http://dx.doi.org/10.1038/nmat3361 |