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Independent and functional validation of a multi-tumour-type proliferation signature
BACKGROUND: Previously we demonstrated that an mRNA signature reflecting cellular proliferation had strong prognostic value. As clinical applicability of signatures can be controversial, we sought to improve our marker’s clinical utility by validating its biological relevance, reproducibility in ind...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405210/ https://www.ncbi.nlm.nih.gov/pubmed/22722312 http://dx.doi.org/10.1038/bjc.2012.269 |