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Independent and functional validation of a multi-tumour-type proliferation signature

BACKGROUND: Previously we demonstrated that an mRNA signature reflecting cellular proliferation had strong prognostic value. As clinical applicability of signatures can be controversial, we sought to improve our marker’s clinical utility by validating its biological relevance, reproducibility in ind...

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Detalles Bibliográficos
Autores principales: Starmans, M H W, Lieuwes, N G, Span, P N, Haider, S, Dubois, L, Nguyen, F, van Laarhoven, H W, Sweep, F C G J, Wouters, B G, Boutros, P C, Lambin, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405210/
https://www.ncbi.nlm.nih.gov/pubmed/22722312
http://dx.doi.org/10.1038/bjc.2012.269