PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma

BACKGROUND: PIM serine/threonine kinases are often highly expressed in haematological malignancies. We have shown that PIM inhibitors reduced the survival and migration of leukaemic cells. Here, we investigated PIM kinases in diffuse large B-cell lymphoma (DLBCL) biopsy samples and DLBCL cell lines....

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Detalles Bibliográficos
Autores principales: Brault, L, Menter, T, Obermann, E C, Knapp, S, Thommen, S, Schwaller, J, Tzankov, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405213/
https://www.ncbi.nlm.nih.gov/pubmed/22722314
http://dx.doi.org/10.1038/bjc.2012.272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405213/
https://www.ncbi.nlm.nih.gov/pubmed/22722314
http://dx.doi.org/10.1038/bjc.2012.272

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