Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation

BACKGROUND: Our earlier reports demonstrated that membrane-bound semaphorin 5A (SEMA5A) is expressed in aggressive pancreatic cancer cells and tumours, and promotes tumour growth and metastasis. In this study, we examine whether (1) pancreatic cancer cells secrete SEMA5A and (2) that secreted SEMA5A...

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Detalles Bibliográficos
Autores principales: Sadanandam, A, Sidhu, S S, Wullschleger, S, Singh, S, Varney, M L, Yang, C-S, Ashour, A E, Batra, S K, Singh, R K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405228/
https://www.ncbi.nlm.nih.gov/pubmed/22782341
http://dx.doi.org/10.1038/bjc.2012.298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405228/
https://www.ncbi.nlm.nih.gov/pubmed/22782341
http://dx.doi.org/10.1038/bjc.2012.298

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