Cargando…

Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling

BACKGROUND: Abnormal proteostasis due to alterations in protein turnover has been postulated to play a central role in several neurodegenerative diseases. Therefore, the development of techniques to quantify protein turnover in the brain is critical for understanding the pathogenic mechanisms of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basak, Jacob M, Kim, Jungsu, Pyatkivskyy, Yuriy, Wildsmith, Kristin R, Jiang, Hong, Parsadanian, Maia, Patterson, Bruce W, Bateman, Randall J, Holtzman, David M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405485/ https://www.ncbi.nlm.nih.gov/pubmed/22512932 http://dx.doi.org/10.1186/1750-1326-7-14

Ejemplares similares

In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS
por: Wildsmith, Kristin R., et al.
Publicado: (2012)

Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS
por: Wildsmith, Kristin R., et al.
Publicado: (2012)

Validation of a single biopsy approach and bolus protein feeding to determine myofibrillar protein synthesis in stable isotope tracer studies in humans
por: Burd, Nicholas A, et al.
Publicado: (2011)

Evidence for impaired amyloid β clearance in Alzheimer's disease
por: Wildsmith, Kristin R, et al.
Publicado: (2013)

Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis
por: Weindl, Daniel, et al.
Publicado: (2016)

In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis
por: Ulrich, Jason D, et al.
Publicado: (2013)

A randomized controlled study to evaluate the effect of bexarotene on amyloid-β and apolipoprotein E metabolism in healthy subjects
por: Ghosal, Kaushik, et al.
Publicado: (2016)

Apolipoprotein E, amyloid-ß clearance and therapeutic opportunities in Alzheimer's disease
por: Kline, Adam
Publicado: (2012)

Insect flight metabolic rate revealed by bolus injection of the stable isotope (13)C
por: Urca, Tomer, et al.
Publicado: (2021)

Amyloid-β Plaques in Clinical Alzheimer’s Disease Brain Incorporate Stable Isotope Tracer In Vivo and Exhibit Nanoscale Heterogeneity
por: Wildburger, Norelle C., et al.
Publicado: (2018)

Stable isotope shifted matrices enable the use of low mass ion precursor scanning for targeted metabolite identification
por: Reilly, Charles B, et al.
Publicado: (2011)

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
por: Garai, Kanchan, et al.
Publicado: (2014)

Apolipoprotein E in Synaptic Plasticity and Alzheimer’s Disease: Potential Cellular and Molecular Mechanisms
por: Kim, Jaekwang, et al.
Publicado: (2014)

The metabolism of human soluble amyloid precursor protein isoforms is quantifiable by a stable isotope labeling-tandem mass spectrometry method
por: Dobrowolska Zakaria, Justyna A., et al.
Publicado: (2022)

Decoding the dynamics of cellular metabolism and the action of 3-bromopyruvate and 2-deoxyglucose using pulsed stable isotope-resolved metabolomics
por: Pietzke, Matthias, et al.
Publicado: (2014)

Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator
por: Flegg, Jennifer A, et al.
Publicado: (2011)

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer’s disease
por: Wolf, Andrew B, et al.
Publicado: (2013)

The parasite clearance curve
por: White, NJ
Publicado: (2011)

Metabolic labeling with stable isotope nitrogen ((15)N) to follow amino acid and protein turnover of three plastid proteins in Chlamydomonas reinhardtii
por: Sauer, Marie-Laure A, et al.
Publicado: (2014)

Plasma amyloid-β42/40 and apolipoprotein E for amyloid PET pre-screening in secondary prevention trials of Alzheimer’s disease
por: Cullen, Nicholas C, et al.
Publicado: (2023)

MIDcor, an R-program for deciphering mass interferences in mass spectra of metabolites enriched in stable isotopes
por: Selivanov, Vitaly A., et al.
Publicado: (2017)

Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels
por: Robert, Jerome, et al.
Publicado: (2017)

Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics
por: Wildsmith, Kristin R, et al.
Publicado: (2014)

Correcting for the effects of natural abundance in stable isotope resolved metabolomics experiments involving ultra-high resolution mass spectrometry
por: Moseley, Hunter NB
Publicado: (2010)

A robust design for identification of the Parasite Clearance Estimator
por: Jamsen, Kris M, et al.
Publicado: (2013)

Morphological analysis of Apolipoprotein E binding to Aβ Amyloid using a combination of Surface Plasmon Resonance, Immunogold Labeling and Scanning Electron Microscopy
por: Islam, Tohidul, et al.
Publicado: (2019)

A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism
por: Zhong, Li, et al.
Publicado: (2016)

An improved pyrite pretreatment protocol for kinetic and isotopic studies
por: Mirzoyan, Natella, et al.
Publicado: (2014)

Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis
por: Kim, Jungsu, et al.
Publicado: (2012)

Accelerated clearance of human red blood cells in a rat transfusion model
por: Straat, M., et al.
Publicado: (2015)

Ultra-sensitive isotope probing to quantify activity and substrate assimilation in microbiomes
por: Kleiner, Manuel, et al.
Publicado: (2023)

Quantitative proteomic analysis of formalin–fixed, paraffin–embedded clear cell renal cell carcinoma tissue using stable isotopic dimethylation of primary amines
por: Weißer, J., et al.
Publicado: (2015)

Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury
por: Main, Bevan S., et al.
Publicado: (2018)

Use of the bolus tracking technique for the tomographic evaluation of the uretero-vesicular junction in dogs and assessment of dose records
por: Longo, Maurizio, et al.
Publicado: (2016)

Parallel isotope differential modeling for instationary 13C fluxomics at the genome scale
por: Zhang, Zhengdong, et al.
Publicado: (2020)

Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's disease
por: Liao, Fan, et al.
Publicado: (2017)

Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models
por: Liao, Fan, et al.
Publicado: (2015)

High-resolution Impedance Manometry Criteria in the Sitting Position Indicative of Incomplete Bolus Clearance
por: Park, Eui Ju, et al.
Publicado: (2014)

Isotope ratio-based quantification of carbon assimilation highlights the role of plastidial isoprenoid precursor availability in photosynthesis
por: Bergman, Matthew E., et al.
Publicado: (2021)

A single column separation method for barium isotope analysis of geologic and hydrologic materials with complex matrices
por: Matecha, R. M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v2uhl3n5198d9oj3a2vanta7so