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Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

Comparison of transcriptomic and proteomic data from pathologically similar multiple sclerosis (MS) lesions reveals down-regulation of CD47 at the messenger RNA level and low abundance at the protein level. Immunohistochemical studies demonstrate that CD47 is expressed in normal myelin and in foamy...

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Detalles Bibliográficos
Autores principales: Han, May H., Lundgren, Deborah H., Jaiswal, Siddhartha, Chao, Mark, Graham, Kareem L., Garris, Christopher S., Axtell, Robert C., Ho, Peggy P., Lock, Christopher B., Woodard, Joslyn I., Brownell, Sara E., Zoudilova, Maria, Hunt, Jack F.V., Baranzini, Sergio E., Butcher, Eugene C., Raine, Cedric S., Sobel, Raymond A., Han, David K., Weissman, Irving, Steinman, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405500/
https://www.ncbi.nlm.nih.gov/pubmed/22734047
http://dx.doi.org/10.1084/jem.20101974