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Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice
Comparison of transcriptomic and proteomic data from pathologically similar multiple sclerosis (MS) lesions reveals down-regulation of CD47 at the messenger RNA level and low abundance at the protein level. Immunohistochemical studies demonstrate that CD47 is expressed in normal myelin and in foamy...
Autores principales: | Han, May H., Lundgren, Deborah H., Jaiswal, Siddhartha, Chao, Mark, Graham, Kareem L., Garris, Christopher S., Axtell, Robert C., Ho, Peggy P., Lock, Christopher B., Woodard, Joslyn I., Brownell, Sara E., Zoudilova, Maria, Hunt, Jack F.V., Baranzini, Sergio E., Butcher, Eugene C., Raine, Cedric S., Sobel, Raymond A., Han, David K., Weissman, Irving, Steinman, Lawrence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405500/ https://www.ncbi.nlm.nih.gov/pubmed/22734047 http://dx.doi.org/10.1084/jem.20101974 |
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