FolX from Pseudomonas aeruginosa is octameric in both crystal and solution

FolX encodes an epimerase that forms one step of the tetrahydrofolate biosynthetic pathway, which is of interest as it is an established target for important drugs. Here we report the crystal structure of FolX from the bacterial opportunistic pathogen Pseudomonas aeruginosa, as well as a detailed an...

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Detalles Bibliográficos
Autores principales: Gabrielsen, Mads, Beckham, Katherine S.H., Cogdell, Richard J., Byron, Olwyn, Roe, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405516/
https://www.ncbi.nlm.nih.gov/pubmed/22575651
http://dx.doi.org/10.1016/j.febslet.2012.03.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405516/
https://www.ncbi.nlm.nih.gov/pubmed/22575651
http://dx.doi.org/10.1016/j.febslet.2012.03.031

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