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A1/Bfl-1 in leukocyte development and cell death

The function of the anti-apoptotic Bcl-2 family member Bcl2a1/Bfl-1/A1 is poorly understood due to the lack of appropriate loss-of-function mouse models and redundant effects with other Bcl-2 pro-survival proteins upon overexpression. Expression analysis of A1 suggests predominant roles in leukocyte...

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Detalles Bibliográficos
Autores principales: Ottina, Eleonora, Tischner, Denise, Herold, Marco J., Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405526/
https://www.ncbi.nlm.nih.gov/pubmed/22342458
http://dx.doi.org/10.1016/j.yexcr.2012.01.021