Cargando…
Dynamics and Calcium Association to the N-Terminal Regulatory Domain of Human Cardiac Troponin C: A Multiscale Computational Study
[Image: see text] Troponin C (TnC) is an important regulatory molecule in cardiomyocytes. Calcium binding to site II in TnC initiates a series of molecular events that result in muscle contraction. The most direct change upon Ca(2+) binding is an opening motion of the molecule that exposes a hydroph...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2012
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405770/ https://www.ncbi.nlm.nih.gov/pubmed/22329450 http://dx.doi.org/10.1021/jp212173f |