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Development of an MRI-visible nonviral vector for siRNA delivery targeting gastric cancer

An antibody-directed nonviral vector, polyethylene glycol-grafted polyethylenimine functionalized with superparamagnetic iron oxide nanoparticles and a gastric cancer-associated CD44v6 single-chain variable fragment (scFv(CD44v6),-PEG-g-PEI-SPION), was constructed as a gastric cancer-targeting and m...

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Detalles Bibliográficos
Autores principales: Chen, Yinting, Wang, Weiwei, Lian, Guoda, Qian, Chenchen, Wang, Lingyun, Zeng, Linjuan, Liao, Chengde, Liang, Biling, Huang, Bing, Huang, Kaihong, Shuai, Xintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405872/
https://www.ncbi.nlm.nih.gov/pubmed/22848158
http://dx.doi.org/10.2147/IJN.S24083