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Intracellular delivery mechanism and brain delivery kinetics of biodegradable cationic bovine serum albumin-conjugated polymersomes

BACKGROUND: A novel brain drug delivery system using cationic bovine serum albumin (CBSA)-conjugated biodegradable polymersomes (CBSA-PO) was prepared, and its intracellular delivery mechanism and brain delivery kinetics were evaluated. METHODS AND RESULTS: Biodegradable poly(ethylene glycol)-poly(ɛ...

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Detalles Bibliográficos
Autores principales: Pang, Zhiqing, Gao, Huile, Chen, Jun, Shen, Shun, Zhang, Bo, Ren, Jinfeng, Guo, Liangran, Qian, Yong, Jiang, Xinguo, Mei, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405875/
https://www.ncbi.nlm.nih.gov/pubmed/22848168
http://dx.doi.org/10.2147/IJN.S32514