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A novel lipid-based nanomicelle of docetaxel: evaluation of antitumor activity and biodistribution

PURPOSE: A lipid-based, nanomicelle-loaded docetaxel (M-DOC) was designed and characterized. Optical imaging was employed to evaluate the pharmacokinetics and antitumor efficacy of docetaxel in vivo. MATERIALS AND METHODS: The M-DOC was prepared using the emulsion-diffusion method. Transmission elec...

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Detalles Bibliográficos
Autores principales: Ma, Mingshu, Hao, Yanli, Liu, Nan, Yin, Zhe, Wang, Lan, Liang, Xingjie, Zhang, Xiaoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405881/
https://www.ncbi.nlm.nih.gov/pubmed/22848167
http://dx.doi.org/10.2147/IJN.S29827