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Engineered hepatitis B virus surface antigen L protein particles for in vivo active targeting of splenic dendritic cells
Dendritic cells (DCs) are key regulators of adaptive T-cell responses. By capturing exogenous antigens and presenting antigen-derived peptides via major histocompatibility complex molecules to naïve T cells, DCs induce antigen-specific immune responses in vivo. In order to induce effective host immu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405891/ https://www.ncbi.nlm.nih.gov/pubmed/22848163 http://dx.doi.org/10.2147/IJN.S32813 |