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F-Box Protein Specificity for G1 Cyclins Is Dictated by Subcellular Localization

Levels of G1 cyclins fluctuate in response to environmental cues and couple mitotic signaling to cell cycle entry. The G1 cyclin Cln3 is a key regulator of cell size and cell cycle entry in budding yeast. Cln3 degradation is essential for proper cell cycle control; however, the mechanisms that contr...

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Detalles Bibliográficos
Autores principales: Landry, Benjamin D., Doyle, John P., Toczyski, David P., Benanti, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405998/
https://www.ncbi.nlm.nih.gov/pubmed/22844257
http://dx.doi.org/10.1371/journal.pgen.1002851