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Structure and Binding Interface of the Cytosolic Tails of αXβ2 Integrin

BACKGROUND: Integrins are signal transducer proteins involved in a number of vital physiological processes including cell adhesion, proliferation and migration. Integrin molecules are hetero-dimers composed of two distinct subunits, α and β. In humans, 18 α and 8 β subunits are combined into 24 diff...

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Detalles Bibliográficos
Autores principales: Chua, Geok-Lin, Tang, Xiao-Yan, Patra, Alok Tanala, Tan, Suet-Mien, Bhattacharjya, Surajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406025/
https://www.ncbi.nlm.nih.gov/pubmed/22844534
http://dx.doi.org/10.1371/journal.pone.0041924