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Structure and Binding Interface of the Cytosolic Tails of αXβ2 Integrin
BACKGROUND: Integrins are signal transducer proteins involved in a number of vital physiological processes including cell adhesion, proliferation and migration. Integrin molecules are hetero-dimers composed of two distinct subunits, α and β. In humans, 18 α and 8 β subunits are combined into 24 diff...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406025/ https://www.ncbi.nlm.nih.gov/pubmed/22844534 http://dx.doi.org/10.1371/journal.pone.0041924 |