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Two-Component Systems Are Involved in the Regulation of Botulinum Neurotoxin Synthesis in Clostridium botulinum Type A Strain Hall

Clostridium botulinum synthesizes a potent neurotoxin (BoNT) which associates with non-toxic proteins (ANTPs) to form complexes of various sizes. The bont and antp genes are clustered in two operons. In C. botulinum type A, bont/A and antp genes are expressed during the end of the exponential growth...

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Detalles Bibliográficos
Autores principales: Connan, Chloé, Brueggemann, Holger, Mazuet, Christelle, Raffestin, Stéphanie, Cayet, Nadège, Popoff, Michel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406050/
https://www.ncbi.nlm.nih.gov/pubmed/22848632
http://dx.doi.org/10.1371/journal.pone.0041848