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Empirical Validation of Pooled Whole Genome Population Re-Sequencing in Drosophila melanogaster

The sequencing of pooled non-barcoded individuals is an inexpensive and efficient means of assessing genome-wide population allele frequencies, yet its accuracy has not been thoroughly tested. We assessed the accuracy of this approach on whole, complex eukaryotic genomes by resequencing pools of lar...

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Detalles Bibliográficos
Autores principales: Zhu, Yuan, Bergland, Alan O., González, Josefa, Petrov, Dmitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406057/
https://www.ncbi.nlm.nih.gov/pubmed/22848651
http://dx.doi.org/10.1371/journal.pone.0041901