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Empirical Validation of Pooled Whole Genome Population Re-Sequencing in Drosophila melanogaster
The sequencing of pooled non-barcoded individuals is an inexpensive and efficient means of assessing genome-wide population allele frequencies, yet its accuracy has not been thoroughly tested. We assessed the accuracy of this approach on whole, complex eukaryotic genomes by resequencing pools of lar...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406057/ https://www.ncbi.nlm.nih.gov/pubmed/22848651 http://dx.doi.org/10.1371/journal.pone.0041901 |