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Shedding of TRAP by a Rhomboid Protease from the Malaria Sporozoite Surface Is Essential for Gliding Motility and Sporozoite Infectivity

Plasmodium sporozoites, the infective stage of the malaria parasite, move by gliding motility, a unique form of locomotion required for tissue migration and host cell invasion. TRAP, a transmembrane protein with extracellular adhesive domains and a cytoplasmic tail linked to the actomyosin motor, is...

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Detalles Bibliográficos
Autores principales: Ejigiri, Ijeoma, Ragheb, Daniel R. T., Pino, Paco, Coppi, Alida, Bennett, Brandy Lee, Soldati-Favre, Dominique, Sinnis, Photini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406075/
https://www.ncbi.nlm.nih.gov/pubmed/22911675
http://dx.doi.org/10.1371/journal.ppat.1002725