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Shedding of TRAP by a Rhomboid Protease from the Malaria Sporozoite Surface Is Essential for Gliding Motility and Sporozoite Infectivity
Plasmodium sporozoites, the infective stage of the malaria parasite, move by gliding motility, a unique form of locomotion required for tissue migration and host cell invasion. TRAP, a transmembrane protein with extracellular adhesive domains and a cytoplasmic tail linked to the actomyosin motor, is...
Autores principales: | Ejigiri, Ijeoma, Ragheb, Daniel R. T., Pino, Paco, Coppi, Alida, Bennett, Brandy Lee, Soldati-Favre, Dominique, Sinnis, Photini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406075/ https://www.ncbi.nlm.nih.gov/pubmed/22911675 http://dx.doi.org/10.1371/journal.ppat.1002725 |
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