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IL-10-Producing Th1 Cells and Disease Progression Are Regulated by Distinct CD11c(+) Cell Populations during Visceral Leishmaniasis

IL-10 is a critical regulatory cytokine involved in the pathogenesis of visceral leishmaniasis caused by Leishmania donovani and clinical and experimental data indicate that disease progression is associated with expanded numbers of CD4(+) IFNγ(+) T cells committed to IL-10 production. Here, combini...

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Detalles Bibliográficos
Autores principales: Owens, Benjamin M. J., Beattie, Lynette, Moore, John W. J., Brown, Najmeeyah, Mann, Jason L., Dalton, Jane E., Maroof, Asher, Kaye, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406093/
https://www.ncbi.nlm.nih.gov/pubmed/22911108
http://dx.doi.org/10.1371/journal.ppat.1002827