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Type I Interferons Promote Fatal Immunopathology by Regulating Inflammatory Monocytes and Neutrophils during Candida Infections

Invasive fungal infections by Candida albicans (Ca) are a frequent cause of lethal sepsis in intensive care unit patients. While a contribution of type I interferons (IFNs-I) in fungal sepsis remains unknown, these immunostimulatory cytokines mediate the lethal effects of endotoxemia and bacterial s...

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Detalles Bibliográficos
Autores principales: Majer, Olivia, Bourgeois, Christelle, Zwolanek, Florian, Lassnig, Caroline, Kerjaschki, Dontscho, Mack, Matthias, Müller, Mathias, Kuchler, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406095/
https://www.ncbi.nlm.nih.gov/pubmed/22911155
http://dx.doi.org/10.1371/journal.ppat.1002811