Tip60 HAT Activity Mediates APP Induced Lethality and Apoptotic Cell Death in the CNS of a Drosophila Alzheimer's Disease Model

Histone acetylation of chromatin promotes dynamic transcriptional responses in neurons that influence neuroplasticity critical for cognitive ability. It has been demonstrated that Tip60 histone acetyltransferase (HAT) activity is involved in the transcriptional regulation of genes enriched for neuro...

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Detalles Bibliográficos
Autores principales: Pirooznia, Sheila K., Sarthi, Jessica, Johnson, Ashley A., Toth, Meridith S., Chiu, Kellie, Koduri, Sravanthi, Elefant, Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406101/
https://www.ncbi.nlm.nih.gov/pubmed/22848598
http://dx.doi.org/10.1371/journal.pone.0041776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406101/
https://www.ncbi.nlm.nih.gov/pubmed/22848598
http://dx.doi.org/10.1371/journal.pone.0041776

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