Tricyclic Pyrazoles. Part 5. Novel 1,4-Dihydroindeno[1,2-c]pyrazole CB2 Ligands Using Molecular Hybridization Based on Scaffold Hopping

In search of new selective CB2 ligands, the synthesis and preliminary biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazole hybrids of the highly potent prototypicals 5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-N-fenchyl-1H-pyrazole-3-carboxamide 1 and 1-(2,4-dichlorophenyl)-6-methyl-N-...

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Detalles Bibliográficos
Autores principales: Murineddu, Gabriele, Asproni, Battistina, Ruiu, Stefania, Deligia, Francesco, Falzoi, Matteo, Pau, Amedeo, Thomas, Brian F, Zhang, Yanan, Pinna, Gérard A, Pani, Luca, Lazzari, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406267/
https://www.ncbi.nlm.nih.gov/pubmed/22876271
http://dx.doi.org/10.2174/1874104501206010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406267/
https://www.ncbi.nlm.nih.gov/pubmed/22876271
http://dx.doi.org/10.2174/1874104501206010001

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