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Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model

Parthenolide (PT), a sesquiterpene lactone derived from the plant feverfew, has pro-apoptotic activity in a number of cancer cell types. We assessed whether PT induces the apoptosis of hepatic stellate cells (HCSs) and examined its effects on hepatic fibrosis in an in vivo model. The effects of PT o...

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Detalles Bibliográficos
Autores principales: Kim, In Hee, Kim, Sang Wook, Kim, Seong Hun, Lee, Seung Ok, Lee, Soo Teik, Kim, Dae-Ghon, Lee, Mi-Jin, Park, Woo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406290/
https://www.ncbi.nlm.nih.gov/pubmed/22581380
http://dx.doi.org/10.3858/emm.2012.44.7.051