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New Treatment Options for Late Na Current, Arrhythmias, and Diastolic Dysfunction
The late Na current is of pathophysiological importance for the heart. Ranolazine is an innovative anti-ischemic and antianginal agent that inhibits the late Na current, thereby reducing the Na-dependent Ca-overload, which improves diastolic tone and oxygen handling during myocardial ischemia. In ad...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Current Science Inc.
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406311/ https://www.ncbi.nlm.nih.gov/pubmed/22767404 http://dx.doi.org/10.1007/s11897-012-0099-3 |