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Altered Death Receptor Signaling Promotes Epithelial-to-Mesenchymal Transition and Acquired Chemoresistance

Altered death receptor signaling and resistance to subsequent apoptosis is an important clinical resistance mechanism. Here, we investigated the role of death receptor resistance in breast cancer progression. Resistance of the estrogen receptor alpha (ER)-positive, chemosensitive MCF7 breast cancer...

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Detalles Bibliográficos
Autores principales: Antoon, James W., Lai, Rongye, Struckhoff, Amanda P., Nitschke, Ashley M., Elliott, Steven, Martin, Elizabeth C., Rhodes, Lyndsay V., Yoon, Nam Seung, Salvo, Virgilio A., Shan, Bin, Beckman, Barbara S., Nephew, Kenneth P., Burow, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406343/
https://www.ncbi.nlm.nih.gov/pubmed/22844580
http://dx.doi.org/10.1038/srep00539