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Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation

BACKGROUND: Tracheal aspirates (TAs) from critically ill neonates accumulate bacterial endotoxin and demonstrate mobilization of endotoxin-binding proteins, but the potential bioactivity of endotoxin in TAs is unknown. We characterized innate immune activation in TAs of mechanically ventilated neona...

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Detalles Bibliográficos
Autores principales: Nathe, Katheryn E., Mancuso, Christy J., Parad, Richard, Van Marter, Linda J., Martin, Camilia R., Stoler-Barak, Liat, Philbin, Victoria J., Phillips, Michele F., Palmer, Christine D., Levy, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406551/
https://www.ncbi.nlm.nih.gov/pubmed/22580716
http://dx.doi.org/10.1038/pr.2012.61