BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair

H2AX, a histone H2A variant, has a key role in the cellular response to DNA double-strand breaks (DSBs). H2AX senses DSBs through rapid serine 139 phosphorylation, concurrently leading to the formation of phospho-(γ)H2AX foci with various proteins. However, in the cells with different sensitivity to...

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Detalles Bibliográficos
Autores principales: Lee, Y Y, Yu, Y B, Gunawardena, H P, Xie, L, Chen, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406578/
https://www.ncbi.nlm.nih.gov/pubmed/22833098
http://dx.doi.org/10.1038/cddis.2012.76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406578/
https://www.ncbi.nlm.nih.gov/pubmed/22833098
http://dx.doi.org/10.1038/cddis.2012.76

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