Photofrin binds to procaspase-3 and mediates photodynamic treatment-triggered methionine oxidation and inactivation of procaspase-3

Diverse death phenotypes of cancer cells can be induced by Photofrin-mediated photodynamic therapy (PDT), which has a decisive role in eliciting a tumor-specific immunity for long-term tumor control. However, the mechanism(s) underlying this diversity remain elusive. Caspase-3 is a critical factor i...

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Detalles Bibliográficos
Autores principales: Hsieh, Y-J, Chien, K-Y, Lin, S-Y, Sabu, S, Hsu, R-M, Chi, L-M, Lyu, P-C, Yu, J-S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406584/
https://www.ncbi.nlm.nih.gov/pubmed/22785533
http://dx.doi.org/10.1038/cddis.2012.85

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406584/
https://www.ncbi.nlm.nih.gov/pubmed/22785533
http://dx.doi.org/10.1038/cddis.2012.85

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