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Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors

The molecular pathology of thymic epithelial tumors (TETs) is largely unknown. Using array comparative genomic hybridization (CGH), we evaluated 59 TETs and identified recurrent patterns of copy number (CN) aberrations in different histotypes. GISTIC algorithm revealed the presence of 126 significan...

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Detalles Bibliográficos
Autores principales: Petrini, I, Meltzer, P S, Zucali, P A, Luo, J, Lee, C, Santoro, A, Lee, H S, Killian, K J, Wang, Y, Tsokos, M, Roncalli, M, Steinberg, S M, Giaccone, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406591/
https://www.ncbi.nlm.nih.gov/pubmed/22825469
http://dx.doi.org/10.1038/cddis.2012.92