𝒟(−)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent

We have recently found that 𝒟(−)lentiginosine, a synthetic iminosugar exerting glucosidase inhibitory activity, but not its natural enantiomer lentiginosine, is endowed with an unexpected, pro-apoptotic activity. Here, we investigated mechanisms involved in apoptosis induced by 𝒟−)lentiginosine in M...

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Detalles Bibliográficos
Autores principales: Minutolo, A, Grelli, S, Marino-Merlo, F, Cordero, F M, Brandi, A, Macchi, B, Mastino, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406596/
https://www.ncbi.nlm.nih.gov/pubmed/22833097
http://dx.doi.org/10.1038/cddis.2012.97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406596/
https://www.ncbi.nlm.nih.gov/pubmed/22833097
http://dx.doi.org/10.1038/cddis.2012.97

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