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𝒟(−)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent
We have recently found that 𝒟(−)lentiginosine, a synthetic iminosugar exerting glucosidase inhibitory activity, but not its natural enantiomer lentiginosine, is endowed with an unexpected, pro-apoptotic activity. Here, we investigated mechanisms involved in apoptosis induced by 𝒟−)lentiginosine in M...
Autores principales: | Minutolo, A, Grelli, S, Marino-Merlo, F, Cordero, F M, Brandi, A, Macchi, B, Mastino, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406596/ https://www.ncbi.nlm.nih.gov/pubmed/22833097 http://dx.doi.org/10.1038/cddis.2012.97 |
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