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Coupling of Voltage-Sensors to the Channel Pore: A Comparative View
The activation of voltage-dependent ion channels is initiated by potential-induced conformational rearrangements in the voltage-sensor domains that propagates to the pore domain (PD) and finally opens the ion conduction pathway. In potassium channels voltage-sensors are covalently linked to the pore...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406610/ https://www.ncbi.nlm.nih.gov/pubmed/22866036 http://dx.doi.org/10.3389/fphar.2012.00145 |