Retigeric Acid B Attenuates the Virulence of Candida albicans via Inhibiting Adenylyl Cyclase Activity Targeted by Enhanced Farnesol Production

Candida albicans, the most prevalent fungal pathogen, undergoes yeast-to-hyphal switch which has long been identified as a key fungal virulence factor. We showed here that the lichen-derived small molecule retigeric acid B (RAB) acted as an inhibitor that significantly inhibited the filamentation of...

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Detalles Bibliográficos
Autores principales: Chang, Wenqiang, Li, Ying, Zhang, Li, Cheng, Aixia, Lou, Hongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406657/
https://www.ncbi.nlm.nih.gov/pubmed/22848547
http://dx.doi.org/10.1371/journal.pone.0041624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406657/
https://www.ncbi.nlm.nih.gov/pubmed/22848547
http://dx.doi.org/10.1371/journal.pone.0041624

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