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Rhinocetin, a Venom-derived Integrin-specific Antagonist Inhibits Collagen-induced Platelet and Endothelial Cell Functions

Snaclecs are small non-enzymatic proteins present in viper venoms reported to modulate hemostasis of victims through effects on platelets, vascular endothelial, and smooth muscle cells. In this study, we have isolated and functionally characterized a snaclec that we named “rhinocetin” from the venom...

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Detalles Bibliográficos
Autores principales: Vaiyapuri, Sakthivel, Hutchinson, E. Gail, Ali, Marfoua S., Dannoura, Abeer, Stanley, Ronald G., Harrison, Robert A., Bicknell, Andrew B., Gibbins, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406708/
https://www.ncbi.nlm.nih.gov/pubmed/22689571
http://dx.doi.org/10.1074/jbc.M112.381483