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Akt (protein kinase B) isoform phosphorylation and signaling downstream of mTOR (mammalian target of rapamycin) in denervated atrophic and hypertrophic mouse skeletal muscle

BACKGROUND: The present study examines the hypothesis that Akt (protein kinase B)/mTOR (mammalian target of rapamycin) signaling is increased in hypertrophic and decreased in atrophic denervated muscle. Protein expression and phosphorylation of Akt1, Akt2, glycogen synthase kinase-3beta (GSK-3beta),...

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Detalles Bibliográficos
Autores principales: Norrby, Marlene, Evertsson, Kim, Fjällström, Ann-Kristin, Svensson, Anna, Tågerud, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406959/
https://www.ncbi.nlm.nih.gov/pubmed/22657251
http://dx.doi.org/10.1186/1750-2187-7-7