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Peripheral blood lymphocytes from low-grade squamous intraepithelial lesions patients recognize vaccine antigens in the presence of activated dendritic cells, and produced high levels of CD8 + IFNγ + T cells and low levels of IL-2 when induced to proliferate

BACKGROUND: Most infections with human papillomavirus (HPV) are resolved without clinical intervention, but a minority evolves into chronic lesions of distinct grades, including cervical-uterine cancer. It is known that in most cases the immune system mediates elimination of HPV infection. However,...

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Detalles Bibliográficos
Autores principales: Hernández-Montes, Jorge, Rocha-Zavaleta, Leticia, Monroy-García, Alberto, Weiss-Steider, Benny, Zaragoza-Ortega, María del Carmen, Cruz-Talonia, Fernando, y Cruz, Omar Cruz, Bonifaz-Alfonso, Laura, Chávez-Rueda, Adriana Karina, Rojo-Aguilar, Martha Patricia, Legorreta-Haquet, María Victoria, Mora-García, María de Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406962/
https://www.ncbi.nlm.nih.gov/pubmed/22642942
http://dx.doi.org/10.1186/1750-9378-7-12