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Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses

BACKGROUND: RGS17 and RGS20 encode two members of the regulator of G-protein signaling RGS-Rz subfamily. Variation in these genes may alter their transcription and thereby influence the function of G protein-coupled receptors, including opioid receptors, and modify risk for substance dependence. MET...

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Detalles Bibliográficos
Autores principales: Zhang, Huiping, Wang, Fan, Kranzler, Henry R, Anton, Raymond F, Gelernter, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406967/
https://www.ncbi.nlm.nih.gov/pubmed/22591552
http://dx.doi.org/10.1186/1744-9081-8-23