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Plant HDAC inhibitor chrysin arrest cell growth and induce p21(WAF1) by altering chromatin of STAT response element in A375 cells
BACKGROUND: Chrysin and its analogues, belongs to flavonoid family and possess potential anti-tumour activity. The aim of this study is to determine the molecular mechanism by which chrysin controls cell growth and induce apoptosis in A375 cells. METHODS: Effect of chrysin and its analogues on cell...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407000/ https://www.ncbi.nlm.nih.gov/pubmed/22591439 http://dx.doi.org/10.1186/1471-2407-12-180 |