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Plant HDAC inhibitor chrysin arrest cell growth and induce p21(WAF1) by altering chromatin of STAT response element in A375 cells

BACKGROUND: Chrysin and its analogues, belongs to flavonoid family and possess potential anti-tumour activity. The aim of this study is to determine the molecular mechanism by which chrysin controls cell growth and induce apoptosis in A375 cells. METHODS: Effect of chrysin and its analogues on cell...

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Detalles Bibliográficos
Autores principales: Pal-Bhadra, Manika, Ramaiah, M Janaki, Reddy, T Lakshminarayan, Krishnan, Anita, Pushpavalli, SNCVL, Babu, K Suresh, Tiwari, Ashok K, Rao, J Madhusudana, Yadav, Jhillu S, Bhadra, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407000/
https://www.ncbi.nlm.nih.gov/pubmed/22591439
http://dx.doi.org/10.1186/1471-2407-12-180