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Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle

BACKGROUND: The expression of PDK4 is elevated by diabetes, fasting and other conditions associated with the switch from the utilization of glucose to fatty acids as an energy source. It is previously shown that peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a master regulator...

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Detalles Bibliográficos
Autores principales: Rinnankoski-Tuikka, Rita, Silvennoinen, Mika, Torvinen, Sira, Hulmi, Juha J, Lehti, Maarit, Kivelä, Riikka, Reunanen, Hilkka, Kainulainen, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407034/
https://www.ncbi.nlm.nih.gov/pubmed/22682013
http://dx.doi.org/10.1186/1743-7075-9-53