Association of Eleven Common, Low-Penetrance Colorectal Cancer Susceptibility Genetic Variants at Six Risk Loci with Clinical Outcome

BACKGROUND: Low-penetrance genetic variants have been increasingly recognized to influence the risk of tumor development. Risk variants for colorectal cancer (CRC) have been mapped to chromosome positions 8q23.3, 8q24, 9p24.1, 10p14, 11q23, 14q22.2, 15q13, 16q22.1, 18q21, 19q13.1 and 20p12.3. In par...

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Detalles Bibliográficos
Autores principales: Hoskins, Janelle M., Ong, Pei-Shi, Keku, Temitope O., Galanko, Joseph A., Martin, Christopher F., Coleman, Clint A., Wolfe, Michelle, Sandler, Robert S., McLeod, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407042/
https://www.ncbi.nlm.nih.gov/pubmed/22848671
http://dx.doi.org/10.1371/journal.pone.0041954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407042/
https://www.ncbi.nlm.nih.gov/pubmed/22848671
http://dx.doi.org/10.1371/journal.pone.0041954

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