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The Mph1 Helicase Can Promote Telomere Uncapping and Premature Senescence in Budding Yeast
Double strand breaks (DSBs) can be repaired via either Non-Homologous End Joining (NHEJ) or Homology directed Repair (HR). Telomeres, which resemble DSBs, are refractory to repair events in order to prevent chromosome end fusions and genomic instability. In some rare instances telomeres engage in Br...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407055/ https://www.ncbi.nlm.nih.gov/pubmed/22848695 http://dx.doi.org/10.1371/journal.pone.0042028 |