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Influence of GABA(A) Receptor α Subunit Isoforms on the Benzodiazepine Binding Site
Classical benzodiazepines, such as diazepam, interact with α(x)β(2)γ(2) GABA(A) receptors, x = 1, 2, 3, 5 and modulate their function. Modulation of different receptor isoforms probably results in selective behavioural effects as sedation and anxiolysis. Knowledge of differences in the structure of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407089/ https://www.ncbi.nlm.nih.gov/pubmed/22848717 http://dx.doi.org/10.1371/journal.pone.0042101 |