Regulation of Lean Mass, Bone Mass, and Exercise Tolerance by the Central Melanocortin System

Signaling via the type 4-melanocortin receptor (MC4R) is an important determinant of body weight in mice and humans, where loss of function mutations lead to significant obesity. Humans with mutations in the MC4R experience an increase in lean mass. However, the simultaneous accrual of fat mass in s...

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Detalles Bibliográficos
Autores principales: Braun, Theodore P., Orwoll, Benjamin, Zhu, Xinxia, Levasseur, Peter R., Szumowski, Marek, Nguyen, My Linh T., Bouxsein, Mary L., Klein, Robert F., Marks, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407101/
https://www.ncbi.nlm.nih.gov/pubmed/22848742
http://dx.doi.org/10.1371/journal.pone.0042183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407101/
https://www.ncbi.nlm.nih.gov/pubmed/22848742
http://dx.doi.org/10.1371/journal.pone.0042183

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