Methylene Blue Protects against TDP-43 and FUS Neuronal Toxicity in C. elegans and D. rerio

The DNA/RNA-binding proteins TDP-43 and FUS are found in protein aggregates in a growing number of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and related dementia, but little is known about the neurotoxic mechanisms. We have generated Caenorhabditis elegans and zebrafi...

Descripción completa

Detalles Bibliográficos
Autores principales: Vaccaro, Alexandra, Patten, Shunmoogum A., Ciura, Sorana, Maios, Claudia, Therrien, Martine, Drapeau, Pierre, Kabashi, Edor, Parker, J. Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407135/
https://www.ncbi.nlm.nih.gov/pubmed/22848727
http://dx.doi.org/10.1371/journal.pone.0042117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407135/
https://www.ncbi.nlm.nih.gov/pubmed/22848727
http://dx.doi.org/10.1371/journal.pone.0042117

Ejemplares similares