Downregulation of the NHE3-Binding PDZ-Adaptor Protein PDZK1 Expression during Cytokine-Induced Inflammation in Interleukin-10–Deficient Mice

BACKGROUND: Impaired salt and water absorption is an important feature in the pathogenesis of diarrhea in inflammatory bowel disease (IBD). We analyzed the expression of proinflammatory cytokines in the infiltrating immune cells and the function and expression of the Na(+)/H(+) exchanger isoform 3 (...

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Detalles Bibliográficos
Autores principales: Lenzen, Henrike, Lünnemann, Maria, Bleich, Andre, Manns, Michael P., Seidler, Ursula, Jörns, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407152/
https://www.ncbi.nlm.nih.gov/pubmed/22848392
http://dx.doi.org/10.1371/journal.pone.0040657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407152/
https://www.ncbi.nlm.nih.gov/pubmed/22848392
http://dx.doi.org/10.1371/journal.pone.0040657

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