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Upregulation of the Coagulation Factor VII Gene during Glucose Deprivation Is Mediated by Activating Transcription Factor 4

BACKGROUND: Constitutive production of blood coagulation proteins by hepatocytes is necessary for hemostasis. Stressful conditions trigger adaptive cellular responses and delay processing of most proteins, potentially affecting plasma levels of proteins secreted exclusively by hepatocytes. We examin...

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Detalles Bibliográficos
Autores principales: Cronin, Katherine R., Mangan, Thomas P., Carew, Josephine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407153/
https://www.ncbi.nlm.nih.gov/pubmed/22848420
http://dx.doi.org/10.1371/journal.pone.0040994