Evaluation of Persistence of Resistant Variants with Ultra-Deep Pyrosequencing in Chronic Hepatitis C Patients Treated with Telaprevir

BACKGROUND & AIMS: Telaprevir, a hepatitis C virus NS3/4A protease inhibitor has significantly improved sustained viral response rates when given in combination with pegylated interferon alfa-2a and ribavirin, compared with current standard of care in hepatitis C virus genotype 1 infected patien...

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Detalles Bibliográficos
Autores principales: Thomas, Xiomara V., de Bruijne, Joep, Sullivan, James C., Kieffer, Tara L., Ho, Cynthia K. Y., Rebers, Sjoerd P., de Vries, Michel, Reesink, Hendrik W., Weegink, Christine J., Molenkamp, Richard, Schinkel, Janke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407168/
https://www.ncbi.nlm.nih.gov/pubmed/22848441
http://dx.doi.org/10.1371/journal.pone.0041191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407168/
https://www.ncbi.nlm.nih.gov/pubmed/22848441
http://dx.doi.org/10.1371/journal.pone.0041191

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